Molecularly imprinted polymers and their use as antidandruff agents

Process according to the preceding claim, characterized in that the basic ethylene monomer comprising one amine group is chosen from:

• (meth)acrylates and (meth)acrylamides having an amine group having formula (I):
• in which R1 denotes H or methyl, X denotes O or NH, R denotes a divalent C1-C4 alkylene group,
• Z denotes an —NR2R3 or —N+R2R3R4 group, X−R2, R3 and R4 denoting independently of each other H or a C1-C4 alkyl,
• X− being an anion chosen from halides, (C2-C6)alkyl sulfates, phosphates, (C2-C6)alkyl- or (C2-C6)alkyl (C6-C10)aryl sulfonates, acetate anions, lactate anions;
• N-(meth)acryloyl-p-aminobenzamidine having formula (II):
• in which R′1 denotes H or methyl, and R′2, R′3, R′4 denote, independently of each other, H or a C1-C4 alkyl group;
• styryl amidines having formula (III):
• in which R5, R6, R7 denote, independently of each other, H or a C1-C4 alkyl group;
• amino styrenes having formula (IV):
• in which Z′ denotes an —NR8R9 or —N+R8R9R10X− group
• R8, R9 and R10 denote, independently of each other, H or a C1-C4 alkyl;
• X− being an anion chosen from halides or (C2-C6)alkyl sulfates, phosphates, (C2-C6)alkyl- or (C2-C6)alkyl (C6-C10)aryl sulfonates, acetate anions, lactate anions;
• W denotes a R′″ or OR′″ group, R′″ being a C1-C4 alkyl group;
• n being an integer equal to 0, 1 or 2;
• vinylpyridines having formula (V):
• in which Y denotes a R′″ or OR′″ group, R′″ being a C1-C4 alkyl group;
• mn being an integer equal to 0, 1 or 2.

Process according to any one of the preceding claims, characterized in that the crosslinking agent comprising at least 2 polymerizable ethylene unsaturations is chosen from monomers having the following formula (C3) or (C4):

• in which:
• A is a phenyl optionally substituted by —COOH;
• R8, the same or different, represents a hydrogen atom or a linear or branched (C1-C8)alkyl group, preferably C1-C6 such as methyl;
• X1 and X2, the same or different, are as defined previously;
• preferably X1=O or NH, and X2=O;
• and more particularly X1=X2=an oxygen atom, or else X1 forms a bond;
• W represents:
• i) either a 5- or 6-membered heteroaryl group such as pyridinyl or a 5- to 8-membered heterocycloalkyl group comprising at least one oxygen atom such as tetrahydrofuryl, piperazynyl or hexahydrofuro[3,2-b]furanyl, ii) or a *-A-(CR9R10)x-A* group when w is 2, with A as defined previously, R9 and R10, the same or different, representing a hydrogen atom or a (C1-C6)alkyl group such as methyl, x represents an integer comprised between 0 and 10 inclusive, preferably x=1 and * represents the attachment point to the —X1—C(X2)—C(═CH2)—R8 groups;
• iii) or a linear or branched polyvalent hydrocarbon-based chain, preferably di or trivalent, saturated or unsaturated, preferably saturated, comprising from 1 to 20 carbon atoms optionally substituted by a hydroxy group or by a phenyl group;
• n represents an integer comprised between 0 and 5 inclusive;
• more particularly between 0 and 3, such as n=0 or 1;
• u and w represent an integer comprised between 2 and 10 inclusive, more particularly between 2 and 5, such as u=2 and w=2 or 3.

Process according to one of the preceding claims, characterized in that the crosslinking agent comprising at least 2 polymerizable ethylene unsaturations is chosen from:

• Name
• Structure
• Styrene/divinyl benzene
• Diisopropyl benzene
• 1,3-phenylene diacrylamide;
• 1,4-phenylene diacrylamide
• N,N′-1,3-phenylenebis(2-methyl-2- propenamide);
• N,N′-1,4- phenylenebis(2-methyl-2- propenamide)
• 3,5-bisacrylamido-benzoic acid where R″ are identical and equal to H;
• and 3,5-bismethylacrylamido- benzoic acid where R″ are identical and equal to CH3
• 2,6-bisacryloylamidopyridine where R″ are identical and equal to H;
• 2,6- bismethylacryloylamidopyridine where R″ are identical and equal to CH3
• 1,4-diacryloylpiperazine where R″ are identical and equal to H;
• 1,4-dimethylacryloylpiperazine where R″ are identical and equal to CH3
• Ethylene glycol dimethacrylate where R″ are identical and equal to CH3 (EGDMA);
• Diacrylate ethylene glycol where R″ are identical and equal to H
• Tetramethylene dimethacrylate where R″ are identical and equal to CH3;
• Tetramethylene diacrylate where R″ are identical and equal to H
• Hexamethylene dimethacrylate where R″ are identical and equal to CH3 and Hexamethylene diacrylate where R″ are identical and equal to H
• Anhydroerythritoldimethacrylate where R″ are identical and equal to CH3 and Anhydroerythritoldiacrylate where R″ are identical and equal to H
• 1,4;3,6-dianhydro-p-sorbitol- 2,5-dimethacrylate where R″ are identical and equal to CH3;
• 1,4;3,6-dianhydro-p-sorbitol- 2,5-diacrylate where R″ are identical and equal to H
• Isopropylenebis(1,4- phenylene)-dimethacrylate where R″ are identical and equal to CH3;
• Isopropylenebis(1,4- phenylene)-diacrylate R″ are identical and equal to H
• 2,2-bis(Hydroxymethyl)butanol trimethacrylate where R″ are identical and equal to CH3 (TRIM);
• 2,2-bis(Hydroxymethyl) butanol triacrylate R″ are identical and equal to H
• Pentaerythritol triacrylate where R″ are identical and equal to H;
• Pentaerythritol trimethacrylate where R″ are identical and equal to CH3
• Pentaerythritol tetraacrylate where R″ are identical and equal to H (PETRA);
• Pentaerythritol tetramethacrylate where R″ are identical and equal to CH3
• N,O-bismethacryloyl- ethanolamine where Rc is equal to ethylene and R″ are identical and equal to CH3
• N,N′-methylene-bis-acrylamide where Rc = CH2 (MDAA);
• or N,N-1,2-ethanediylbis(2-methyl- 2-propenamide) N,N′-ethylene-bis- acrylamide where Rc =CH2—CH2;
• N,N′-butylene-bis-acrylamide where Rc = CH2—CH2—CH2—CH2;
• N,N′-hexylene-bis-acrylamide
• where Rc =
• CH2—CH2—CH2—CH2—CH2—CH2