Back to results
US 2015/0316555 A1Published application
Devices and methods for enrichment and alteration of circulating tumor cells and other particles
AssigneeGPB Scientific, LLC
InventorsMartin FUCHS, Ying-Xin WANG, Yi-Shiuan HUANG, Neil X. KRUEGER
Life of this patent
Estimating the term…
Abstract
The invention features devices and methods for detecting, enriching, and analyzing circulating tumor cells and other particles. The invention further features methods of diagnosing a condition, e.g., cancer, in a subject by analyzing a cellular sample from the subject.
Claims36
A device for cell enrichment comprising:
- a) a receptacle;
- b) a lid detachably attached to said receptacle, said lid comprising a functionalized lid surface, wherein said functionalized lid surface comprises one or more capture moieties that selectively capture a first cell from a cellular sample, and wherein said lid is configured to fit within said receptacle;
- and
- c) a sample mobilizer coupled to either said receptacle or said lid.
1 more element
A method for enriching one or more first cells from a cellular sample, said method comprising the steps of:
- a) placing said cellular sample in a device comprising:
- i) a receptacle;
- ii) a lid detachably attached to said receptacle, said lid comprising at least one functionalized lid surface, wherein said functionalized lid surface comprises one or more capture moieties that selectively capture said first cells from said cellular sample, and wherein said lid is configured to fit within said receptacle;
- and
- iii) a sample mobilizer coupled to either said receptacle or said lid;
- b) covering said cellular sample with said lid;
- c) mobilizing said sample using said sample mobilizer;
- and
- d) removing said lid from said receptacle.
6 more elements
Dependencies are inferred from the claim text.