Using a field effect device for identifying translocating charge-tagged molecules in a nanopore sequencing device
AssigneeCalifornia Institute of Technology
InventorsAndres JARAMILLO-BOTERO, William A. GODDARD, III
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Abstract
A detector apparatus includes a field-effect transistor configured to undergo a change in amplitude of a source-to-drain current when at least a portion of a charge-tagged molecule translocates through the nanopore. In some implementations, the field-effect transistor is a carbon nanotube field effect transistor and the nanopore is located in a membrane. In other implementations, the field-effect transistor is a carbon nanotube field effect transistor and the nanopore is implemented in the form of a nano-channel in a semiconductor layer.
Claims7
A detector apparatus comprising:
- a field-effect transistor having a planar gate terminal;
- and
- a semiconductor layer comprising a nano-channel with a first portion of the nano-channel abutting a major surface of the planar gate terminal.
Dependencies are inferred from the claim text.