An apparatus for detecting a component in a sample
AssigneeRadiometer Medical ApS
InventorsWilly Lindegaard ANDERSEN, Heine HANSEN, Oluf DANNEVANG, Ole Munch HANSEN
Life of this patent
Estimating the term…
Abstract
An apparatus for detecting a first component in a sample, the first component being responsive to at least radiation of a first wavelength, the sample comprising the first component and a second component responsive to at least radiation of a second wavelength.
Claims34
An apparatus for detecting a component in a sample comprising, a first component being responsive to at least radiation of a first wavelength, the sample comprising the first component and a second component responsive to at least radiation of a second wavelength, the apparatus comprising;
- at least one radiation source configured to direct radiation towards the sample;
- at least one radiation detector configured to detect radiation of at least the first and the second wavelength, said detected radiation having propagated along a radiation path through at least a portion of the sample;
- and
- a processing unit operable to receive at least one detector signal from the at least one radiation detector indicative of the detected radiation, and to
- determine an estimated path length of the radiation path at least from a determined absorbance by the sample of radiation at the second wavelength;
- determine an estimated concentration of the first component at least from a determined absorbance by the sample of radiation at the first wavelength and from the estimated path length;
- determine a corrected concentration of the first component at least from the estimated concentration and from a correction term indicative of a corrected path length corrected for a presence of the first component using the estimated concentration.
A method for determining a concentration of a component in a sample comprising, a first component being responsive to at least radiation of a first wavelength, the sample comprising the first component and a second component responsive to at least radiation of a second wavelength, the method comprising:
- receiving a measured first absorbance of the sample at at least the first wavelength and a measured second absorbance of the sample at at least the second wavelength;
- determining, at least from the second absorbance, an estimated path length of a radiation path along which the radiation has propagated through the sample;
- determining an estimated concentration of the first component at least from the first absorbance and from the estimated path length;
- determining a corrected concentration of the first component at least from the estimated concentration and from a correction term indicative of a corrected path length corrected for a presence of the first component using the estimated concentration.
A method for determining a path length of a radiation path along which radiation has propagated through a sample comprising:
- the sample comprising a first component responsive to radiation at at least a first wavelength, and a second component responsive to radiation at at least a second wavelength, the method comprising:
- receiving a measured first absorbance of the sample at at least the first wavelength, and a measured second absorbance of the sample at at least the second wavelength;
- determining, at least from the second absorbance, an estimated path length of a radiation path along which the radiation has propagated through the sample;
- determining an estimated concentration of the first component at least from the first absorbance and from the estimated path length;
- correcting the estimated path length for a presence of the first component using the estimated concentration of the first component.
Dependencies are inferred from the claim text.