Novel probes to quantify the relative importance of ion and particle uptake when assessing nanoparticle bioavailability

Abstract

A core-shell nanoparticle is provided that includes a core comprising a first isotope of an element; an isolation layer surrounding the core; and a shell layer surrounding the isolation layer, wherein the shell layer comprises a second isotope of the element, with the first isotope being different than the second isotope. Methods are also provided for forming such core-shell nanoparticles.

Dependencies are inferred from the claim text.