Methods of screening for cell proliferation or neoplastic disorders
AssigneesThe Johns Hopkins University, National Institute of Health
InventorsAndrew P. Feinberg, Christine A. Iacobuzio-Donahue, Dan L. Longo, Minoru Ko
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Abstract
The invention relates to methods and compositions for identifying subjects having, or predisposed to having, a neoplastic or cell proliferation or neoplastic disorder. The methods are applicable to any type of tissue sample and can be conducted on otherwise normal tissue.
Claims25
A method of determining predisposition of a subject to developing a neoplastic or cell proliferation disorder comprising determining the ratio of undifferentiated to differentiated cells in the same or different sample from the subject, wherein the ratio of undifferentiated to differentiated cells, as compared to a reference ratio, is indicative of a predisposition for developing a neoplastic or cell proliferation disorder.
Dependencies are inferred from the claim text.