System and method for dna sequencing and blood chemistry analysis
AssigneeNanomedical Diagnostics, Inc.
InventorBRETT GOLDSMITH
Life of this patent
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Abstract
A DNA sequencing and blood chemistry analysis device is provided including one or more sensor chips and one or more sample wells, wherein each sample well is configured to form a seal with one of the sensors. The one or more sensor chips may comprise Graphene transistors, and each transistor having an associated sequencing probe. The sensor chips interact with a biological sample introduced into the sample well, wherein changes in the current, transconductance, and resistance of the Graphene transistors are indicative of a DNA binding process. Based on the associated sequencing probes, the DNA sequence present in a biological sample can be identified.
Claims20
A system for biological sample analysis comprising:
- a biological sample sensor comprising a plurality of transistors, wherein at least one transistor comprises Graphene and whereby electrical properties of the at least one transistor change in response to contact with a DNA sequence;
- and
- a sample well having a bottom portion, wherein the sample well is in fluidic communication with the biological sample sensor.
The system of claim 7, wherein the electrical properties measuring device is an amp-meter, a voltmeter, or a computer.
A method for biological sample analysis, comprising:
- introducing a biological sample into a sample well, the sample well comprising a sensor;
- applying a voltage to the sensor, wherein the sensor comprises a plurality of sequencing probes and a plurality of Graphene transistors;
- measuring an electrical property of the sensor;
- identifying changes in the electrical property;
- identifying a change in pH of the suspension based on the change in the electrical property;
- and
- identifying a DNA sequence present in the suspension based on the change in pH.
A system for biological sample analysis comprising:
- a sensing section including a sensor chip comprising a plurality of transistors and a plurality of sequencing probes, wherein at least one of the transistors comprises Graphene;
- a plate section including a biological sample well, wherein the biological sample well is in fluidic communication with the sensor chip;
- and
- a processing section including a processing module.
Dependencies are inferred from the claim text.