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US 2015/0307886 A1Published application
Compositions and methods for modulation of fgfr3 expression
AssigneeRoche Innovation Center Copenhagen A/S
InventorsMaj Hedtjarn, Soren Ottosen
Life of this patent
Estimating the term…
Abstract
Disclosed are oligonucleotides which target and hybridize to nucleic acid molecules encoding FGFR3, leading to reduced expression of FGFR3. Reduction in the aberrant expression of FGFR3 is beneficial for the treatment of certain medical disorders, such as achondroplasia.
Claims17
An antisense oligonucleotide 8-25 nucleotides in length comprising one or more nucleotide analogues, wherein said oligonucleotide is capable of hybridising to a region of SEQ ID NO:
- 4 which comprises nucleotide position 1394 of SEQ ID NO:
- 4.
Dependencies are inferred from the claim text.