Method for manufacturing useful substance in which high-density cultured strain of filamentous fungi is used
AssigneeTohoku University
InventorsKeietsu ABE, Katsuya GOMI, Kei YOSHIMI
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Abstract
An object to be achieved by the present invention is to culture a filamentous fungus at a high density, thereby enabling mass production of a useful substance. The present invention provides a method of producing a substance, including the steps of: culturing a mutant filamentous fungus with no expression of α-1,3-glucan to allow the filamentous fungus to produce a substance; and collecting the resulting substance.
Claims18
A method of producing a substance, comprising the steps of:
- culturing a mutant filamentous fungus with no expression of α-1,3-glucan to allow the filamentous fungus to produce a substance;
- and
- collecting the resulting substance.
A method according to claim 14, wherein the substance is at least one member selected from the group consisting of at least one low-molecular-weight compound selected from the group consisting of penicillin, statins, cephalosporin, kojic acid, citric acid, and malic acid;
- at least one high-molecular-weight compound selected from the group consisting of amylase, cellulase, protease, lipase, peptidase, esterase, and oxidase;
- at least one chemical product selected from the group consisting of an organic acid, a pigment, and an agricultural chemical bulk;
- and substances to be used as pharmaceutical products.
Dependencies are inferred from the claim text.