Back to results
US 2015/0307629 A1Published application
Bispecific antibodies that bind to CD38 and CD3
AssigneeXencor, Inc.
InventorsMatthew Bernett, Seung Chu, Gregory Moore, John Desjarlais
Life of this patent
Estimating the term…
Abstract
The invention provides novel heterodimeric proteins including heterodimeric antibodies.
Claims20
A heterodimeric antibody comprising:
- a) a first heavy chain comprising:
- i) a first variable Fc domain;
- ii) a single chain Fv region (scFv) that binds CD3;
- and
- b) a second heavy chain comprising:
- i) a second Fc variable Fc domain;
- and
- ii) a first variable heavy domain;
- and
- c) a first light chain comprising a first variable light domain and a first constant light domain;
- wherein said first variable heavy domain and said first variable light domain bind to CD38.
8 more elements
Dependencies are inferred from the claim text.