Saturated Nitrogen and N-Acylated Heterocycles Potentiating the Activity of an Active Antibiotic against Mycobacteria

A compound of formula (I):

• in which:
• n is 0 or 1;
• R1 is selected from the group consisting of linear or branched C1-C5 alkyl optionally substituted by fluorine;
• linear or branched C1-C3 alkyl substituted by C3-C6 saturated or unsaturated cycloalkyl;
• cyclopropyl;
• cyclobutyl;
• and cyclopentyl;
• X is N or CH;
• R2 is selected from the group consisting of phenyl, benzyl, phenyl substituted by linear or branched C1-C4 alkyl, benzyl substituted by linear or branched C1-C4 alkyl, phenyl substituted by linear or branched C1-C4 alkyl substituted by fluorine, benzyl substituted by linear or branched C1-C4 alkyl substituted by fluorine, phenyl substituted by one or more substituent selected from Cl, F, CF3, OCH3, and OH, and a six-membered heterocycle comprising one, two or three nitrogen atoms.