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US 2015/0307446 A1Published application
Compositions and methods for the treatment of mucositis
AssigneeCellix Bio Private Limited
InventorMahesh Kandula
Life of this patent
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Abstract
The invention relates to the compounds of formula I or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula I, and methods for the treatment of mucositis may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection. Such compositions may be used to treatment of mucus diseases related to painful inflammation and ulceration of the digestive tract lining and in the mouth.
Claims15
A compound of Formula I:
- or a pharmaceutically acceptable salt, hydrate, polymorph, solvate, prodrug, enantiomer, or stereoisomer thereof, wherein:
- R1 and R3 each independently represent D, —CH3, —OCH3, H, —OCD3,
- R2 and R4 each independently represent
- each a is independently 2, 3 or 7;
- each b is independently 3, 5 or 6;
- each e is independently 1, 2 or 6;
- each c and each d are independently H, D, —OH, —OD, C1-C6-alkyl, —NH2 or —COCH3;
- and
- each n is independently 1, 2, 3, 4 or 5.
6 more elements
Dependencies are inferred from the claim text.