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US 2015/0307442 A1Published application
Prodrugs of gaba analogs, compositions and uses thereof
AssigneeXenoPort, Inc.
InventorMark A. Gallop
Life of this patent
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Abstract
The present invention provides prodrugs of GABA analogs, pharmaceutical compositions of prodrugs of GABA analogs and methods for making prodrugs of GABA analogs. The present invention also provides methods for using prodrugs of GABA analogs and methods for using pharmaceutical compositions of prodrugs of GABA analogs for treating or preventing common diseases and/or disorders.
Claims25
A compound of Formula (I):
- or a pharmaceutically acceptable salt thereof, wherein
- n is 0;
- each of R1, R3, R6 and R7 is hydrogen;
- Y is oxygen;
- and
- R4 and R5, together with the carbon atom to which they are attached, form a cyclobutyl ring that is substituted with an ethanyl-substituted C2-C4 alkenyl moiety.
3 more elements
A compound of Formula (I):
- or a pharmaceutically acceptable salt thereof, wherein
- n is 0;
- each of R1, R3, R6 and R7 is hydrogen;
- Y is oxygen;
- and
- R4 and R5, together with the carbon atom to which they are attached, form a C7-cycloalkenyl ring that is substituted with an ethanyl moiety.
3 more elements
A compound of Formula (XIII):
- wherein each of R3 and R6 is hydrogen;
- R4 and R5, together with the carbon atom to which they are attached, form a cyclobutyl ring that is substituted with an ethanyl-substituted C2-C4 alkenyl moiety.
A compound of Formula (XIII):
- wherein each of R3 and R6 is hydrogen;
- R4 and R5, form a substituted C4-C7 cycloalkyl that is a bicyclic.
Dependencies are inferred from the claim text.