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US 2015/0306597 A1Published application
Redundant microfluidic measurement techniques
AssigneeLightstat, Inc.
InventorAyal Ram
Life of this patent
Estimating the term…
Abstract
Techniques for redundant microfluidic measurements include a substrate in which is formed a microchannel in fluid communication between an entry port and an exit port. The microchannel includes a redundant portion that has multiple sub-channels. A first sub-channel is configured to pass a first fraction of a total flow passing through the entry port. The apparatus also includes a sensor configured to detect separate signals emitted from within the first sub-channel and from within a different sub-channel in the redundant portion of the microchannel.
Claims18
A microfluidic device comprising;
- a substrate in which is formed a microchannel in fluid communication between an entry port and an exit port, wherein
- the microchannel comprises a redundant portion that comprises a plurality of sub-channels, and
- a first sub-channel of the plurality of sub-channels is configured to pass a first fraction of a total flow passing through the entry port;
- and
- a sensor configured to detect separate signals emitted from within the first sub-channel and a different sub-channel of the plurality of sub-channels in the redundant portion of the microchannel.
2 more elements
A method comprising:
- providing a microfluidic device comprising
- a substrate in which is formed a microchannel in fluid communication between an entry port and an exit port, wherein
- the microchannel comprises a redundant portion that comprises a plurality of sub-channels, and
- a first sub-channel of the plurality of sub-channels is configured to pass a first fraction of a total flow passing through the entry port;
- and
- a sensor configured to detect separate signals emitted from within the first sub-channel and a different sub-channel of the plurality of sub-channels in the redundant portion of the microchannel;
- moving a sample fluid from the entry port to the exit port;
- and
- obtaining data from the sensor that indicates separate measurements of the signals emitted from within the first sub-channel and the different sub-channel during an observation period.
6 more elements
A kit comprising:
- a microfluidic device comprising
- a substrate in which is formed a microchannel in fluid communication between an entry port and an exit port, wherein
- the microchannel comprises a redundant portion that comprises a plurality of sub-channels, and
- a first sub-channel of the plurality of sub-channels is configured to pass a first fraction of a total flow passing through the entry port;
- and
- a sensor configured to detect separate signals emitted from within the first sub-channel and a different sub-channel of the plurality of sub-channels in the redundant portion of the microchannel;
- and
- a supply of a reagent selected to produce signals detectable at the sensor based on an analyte in a sample that passes through the microfluidic device.
5 more elements
Dependencies are inferred from the claim text.