Physiological Monitoring-Based Implantable Drug Infusion System
AssigneeMedical Software, LLC
InventorDemir Baykal
Life of this patent
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Abstract
A system and method for physiological monitoring and regulation of a drug infusion device. The system includes an internal compact unit that is implantable in a patient having a pulmonary disorder, the internal unit encasing a power supply, a fluid reservoir, a motor pump, a digital control unit, and a radio frequency transmitter. An infusion catheter is connected to the fluid reservoir and motor pump for automatically infusing a drug into a right ventricle of the patient during a diastole phase of a cardiac cycle. The system includes an external unit for monitoring and storing a plurality of physiological parameters of the patient and for making adjustments to a drug infusion rate.
Claims24
A system for physiological monitoring and regulation of a drug infusion device, comprising:
- an internal compact unit that is implantable in a patient having a pulmonary disorder, the internal unit encasing a power supply, a fluid reservoir, a motor pump, a digital control unit, and a radio frequency transmitter;
- an infusion catheter connected to the fluid reservoir and motor pump for automatically infusing a drug into a right ventricle of the patient during a diastole phase of a cardiac cycle;
- and
- an external unit for monitoring and storing of a plurality of physiological parameters of the patient and for making adjustments to a drug infusion rate.
An infusion catheter for delivery of a drug into a patient having a pulmonary disorder, comprising:
- a radially dense helical structure made of a polyurethane material and having a supporting steel frame to ensure unidirectional flow and prevent clotting within the catheter;
- a hemodynamic pressure sensor mounted on a tip of the catheter for measuring a relative change in hemodynamic pressure over time;
- and
- a biopotential sensor including a biopotential sensing electrode mounted on a tip of the catheter for sensing an electrocardiogram signal of the patient;
- wherein the infusion catheter is connected to a fluid reservoir and a motor pump in an implantable device and automatically infuses a drug into a right ventricle of the patient during a diastole phase of a cardiac cycle at a rate dependent on the measured change in hemodynamic pressure.
A method for hemodynamic monitoring of a patient diagnosed with pulmonary hypertension and infusing a therapeutic drug by an implantable drug infusion device, comprising:
- monitoring the relative change in hemodynamic pressure in a patient's right ventricle over time by a pressure sensor mounted on a tip of an infusion catheter in the implantable device;
- sensing an electrocardiogram signal of the patient by a biopotential sensor including a biopotential sensing electrode mounted on a tip of the infusion catheter;
- infusing the therapeutic drug into the right ventricle during a diastole phase of a cardiac cycle at a rate dependent on the monitored relative change in hemodynamic pressure, the drug being pumped from a fluid reservoir in the implantable device through the infusion catheter into the patient's right ventricle through an infusion port.
Dependencies are inferred from the claim text.