Compositions and methods for detecting complement activation
AssigneeThe Regents of the University of Colorado, a body corporate
InventorsV. Michael Holers, Joshua M. Thurman, Liudmila Kulik
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Abstract
Provided herein, inter alia, are compositions and methods of using the same for detecting complement activation.
Claims51
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An anti-C3d antibody conjugate, comprising a detectable moiety and light chain complementarity determining regions (CDR) 1, 2 and 3, wherein light chain CDR 1 is SEQ ID NO:14, light chain CDR 2 is SEQ ID NO:15 and light chain CDR 3 is SEQ ID NO:16;
- and heavy chain complementarity determining regions (CDR) 1, 2 and 3, wherein heavy chain CDR 1 is SEQ ID NO:17 or SEQ ID NO:27, heavy chain CDR 2 is SEQ ID NO:18 and heavy chain CDR 3 is SEQ ID NO:19 or 29.
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Dependencies are inferred from the claim text.