Back to results
US 2015/0306248 A1Published application
Chimeric vsv-g proteins as nucleic acid transfer vehicles
AssigneeSerendipity Biotech Inc.
InventorSujata Acharjee
Life of this patent
Estimating the term…
Abstract
The design and generation of a number of chimeric VSV-G (or VSV-G variants) proteins are used as transfer vehicles to enhance delivery of nucleic acids like plasmid DNA, single and double stranded DNA and RNA, and antisense oligonucleotides into human and animal cells. These chimeric VSV-G protein-nucleic acid transfer vehicles have widespread applications to deliver nucleic acids for exon skipping and gene delivery for gene replacement in human and animals.
Claims26
A chimeric protein comprising VSV-G and a nucleic acid binding protein.
A method of treating a medical condition in a subject comprising the steps of:
- providing a therapeutic compound comprising a chimeric protein including VSV-G, a nucleic acid binding protein, and at least one nucleic acid;
- and
- administering to said subject a pharmaceutically active amount of said therapeutic compound.
Dependencies are inferred from the claim text.