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US 2015/0306246 A1Published application
Magnetic nanoparticles, composites, suspensions and colloids with high specific absorption rate (sar)
AssigneeTrustees of Dartmouth College
InventorsIan Baker, Katsiaryna Kekalo
Life of this patent
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Abstract
Iron oxide nanoparticles and nanocomposites with organic molecules embedded in their structure, having exceptionally high SAR values, are provided for biological, medical (for example, drug delivery, hyperthermia, etc.) and other uses.
Claims20
A method of synthesizing magnetic nanoparticles (MNPs), comprising
- forming a solution including iron salts and organic chains, wherein the iron salts include a mixture of Fe(II) and Fe(III);
- precipitating, from the iron salts, iron ions in the solution to form iron oxides and iron hydroxides;
- hydrothermally developing MNPs in the solution, where each of the MNPs includes a portion of the iron oxides, a portion of the iron hydroxides, and one or more of the organic chains.
A nanocomposite comprising one or more of magnetic nanoparticles (MNPs), each of the MNPs including:
- iron oxides and iron hydroxides forming a crystal matrix structure;
- and
- organic chains interwoven in the crystal matrix structure.
A magnetic nanoparticle (MNP), comprising:
- oxides and hydroxides of iron in a ratio of Fe(II):Fe(III) greater than 2:1, such that a plurality of copies of the MNP, suspended as colloids in solution, form aggregates that are responsive in a magnetic field and show specific absorption rate (SARI up to 600.0 W/g in a frequency range from 100 Hz-200 kHz at applied field strengths ranging from 10-1500 Oe.
Dependencies are inferred from the claim text.