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US 2015/0306227 A1Published application
Polymers including active agents
AssigneeMicroVention, Inc.
InventorsGregory M. Cruise, Clayton G. Harris, Michael J. Constant
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Abstract
Polymers are described herein comprising: a reaction product of a prepolymer solution including at least one macromer and at least one visualization agent; and an active agent electrostatically bound to the polymer filament or chemically bound to the at least one monomer; wherein the polymer filament does not include metallic support members.
Claims31
A polymer filament comprising:
- a reaction product of a prepolymer solution including at least one macromer and at least one visualization agent;
- and
- a pharmaceutical agent physically entrapped in the polymer filament, electrostatically bound to the polymer filament, or chemically bound to the polymer filament via a degradable linkage.
A method of forming a therapeutic polymer filament comprising:
- reacting a prepolymer solution including at least one macromer, at least one visualization agent, and an active agent electrostatically bound to the polymer filament or chemically bound to the at least one monomer to form the therapeutic polymer filament.
A polymerizable pharmaceutical agent having a structure
- wherein R1 is a pharmaceutical agent;
- p is 0, 1, 2, 3 or 4.
Dependencies are inferred from the claim text.