Aqueous liquid bromfenac composition having preservative efficacy
AssigneeSenju Pharmaceutical Co., Ltd.
InventorsShuichi NISHIHATA, Wakiko ASAYAMA, Suzuka IEMOTO
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Abstract
An aqueous liquid bromfenac composition containing (a) bromfenac or a salt thereof and (b) benzalkonium chloride, characterized by that the composition has preservative efficacy and that the concentration of (b) benzalkonium chloride is higher than 0.0005% and lower than 0.005%.
Claims5
1-16. (canceled)
A method for enhancing the preservative efficacy of an aqueous solution, the method comprising adding bromfenac or a salt thereof to the aqueous solution, wherein the aqueous solution is an aqueous base which contains (a) 0.001 to 0.002% of benzalkonium chloride and (b) 0.025% or higher and lower than 0.25% of a non-ionic surfactant, but does not have sufficient preservative efficacy.
Dependencies are inferred from the claim text.