Soluble Forms of Hendra and Nipah Virus G Glycoprotein
AssigneeThe Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.
InventorsChristopher C. Broder, Katharine N. Bossart
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Abstract
This invention relates to soluble forms of G glycoprotein from Hendra and Nipah virus. In particular, this invention relates to compositions comprising soluble forms of G glycoprotein from Hendra and Nipah virus and also to diagnostic and therapeutic methods using the soluble forms of G glycoprotein from Hendra and Nipah virus. Further, the invention relates to therapeutic antibodies including neutralizing antibodies, and vaccines for the prevention and treatment of infection by Hendra and Nipah viruses.
Claims8
1-40. (canceled)
A method of treating or preventing infection by a Hendra virus in a subject comprising administering to said subject a composition comprising an isolated oligomeric peptide wherein the monomers of the oligomeric peptide consist of the ectodomain of the Hendra virus G protein with an amino acid sequence of SEQ ID NO:
- 16 or a sequence at least 90% identical to SEQ ID NO:
- 16.
Dependencies are inferred from the claim text.