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US 2015/0306204 A1Published application
Vaccine composition for use in immuno-compromised populations
AssigneeEurocine Vaccines AB
InventorsHans Arwidsson, Anna-Karin Maltais
Life of this patent
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Abstract
The invention relates to nasally-administered vaccine compositions effective against infection in immuno-compromised populations. One aspect of the invention is directed to the pediatric use of the vaccine of the invention including a vaccine effective in children against seasonal influenza virus strains. A further aspect of the invention is directed to subjects of all age groups when the composition is for pandemic use.
Claims16
A method of immunizing an immune-compromised subject against influenza for reducing virus shedding comprising:
- administering intranasally to an immuno-compromised subject a composition comprising:
- i) one or more non-live influenza virus antigen(s) selected from the group consisting of whole inactivated virus, split virus, subunit influenza antigen, and recombinant antigens, and
- ii) an adjuvant comprising:
- one or more carboxylic acids,
- an aqueous medium, and
- one or more mono-glycerides.
3 more elements
2-15. (canceled)
Dependencies are inferred from the claim text.