HSP For Use in Treatment for Imiquimod Related Side Effects
AssigneeAlfa Biogene International B.V.
InventorsFederico G. Seifarth, Julia Lax
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Abstract
The invention relates to a healthcare product comprising (i) a component selected from the group of heat shock proteins from alfalfa and heat shock protein hydrolysates from alfalfa, the product further comprising imiquimod or a pharmaceutically acceptable salt or derivative thereof. Further, the invention relates to a healthcare product for use in the prophylactic or therapeutic treatment of a skin disorder. Further, the invention relates to HSP for use for use in preventing the occurrence of a negative-side effect of a treatment with imiquimod, or alleviating such side effect.
Claims18
Healthcare product comprising (i) a component selected from the group of heat shock proteins from alfalfa and heat shock protein hydrolysates from alfalfa, the product further comprising imiquimod
- or a pharmaceutically acceptable salt or derivative thereof.
Healthcare product according to any one of the preceding claims, wherein the healthcare product contains a first container containing a first healthcare composition comprising the heat shock protein or heat shock protein hydrolysate and a second container containing a second healthcare composition comprising imiquimod.
Healthcare product according to any one of the preceding claims, wherein the heat shock protein or heat shock protein hydrolysate is present in a total concentration of 5-1000 μg per mL of the composition in which it is present, in particular of 20-600 μg per mL of healthcare product.
Healthcare product according to any one of the preceding claims, wherein the concentration of imiquimod is in the range of 0.1-10 wt. %.
Healthcare product according to any of the preceding claims for use in the prophylactic or therapeutic treatment of a skin disorder, preferably a skin disorder selected from the group of acne, warts, athlete's foot, Lyme disease, psoriasis, lichen, ichthyosis, keratosis, Darier's disease, pustulosis, herpes zoster, cellulitis, eczema (such as atopic dermatitis), neurodermatitis, herpes, inflammatory skin disorders, skin cancers and children's diseases affecting the skin (such as varicella, rubella, measles).
A heat shock protein, preferably a Hsp 70, more preferably alfalfa Hsp, for use in preventing the occurrence of a negative-side effect of a treatment with imiquimod, or alleviating such side effect.
Dependencies are inferred from the claim text.