Novel oral forms of a phosphonic acid derivative
AssigneeThar Pharmaceuticals, Inc.
InventorsMazen HANNA, Ning SHAN, Miranda CHENEY, David R. WEYNA
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Abstract
Novel solution complexes of zoledronic acid are described which give rise to improved properties of zoledronic acid. The invention includes aqueous solution and molecular complexes of zoledronic acid with and optical isomers of asparagine, histidine, arginine and proline as well as pharmaceutical complexes containing them and methods of treatment using them.
Claims1
A solution complex of a bisphosphonic acid or bisphosphonate comprising a bisphosphonic acid or bisphosphonate with a coformer wherein the aqueous solubility of the bisphosphonic acid or bisphosphonate is improved over the bisphosphonic acid or bisphosphonate alone.
Dependencies are inferred from the claim text.