Propellant-free aerosol formulation for inhalation
AssigneeBoehringer Ingelheim International GmbH
InventorsChristel SCHMELZER, Rainer WEITZEL
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Abstract
The present invention relates to propellant-free aerosol formulations for inhalation containing ipratropium bromide and salbutamol.
Claims8
Propellant-free solution formulations for inhalation which contain the active substances salbutamol, optionally in the form of the pharmacologically acceptable acid addition salts thereof, and ipratropium bromide and optionally further excipients, in a solvent selected from among water, ethanol and water-ethanol mixtures, the weight ratio of salbutamol to ipratropium bromide being in the range from 5:1 to 5.5:1 and the solution formulation containing no other active substances, wherein the formulation contains as further constituents disodium EDTA in an amount of 40 to 60 mg per 100 g as a complexing agent.
(canceled)
Dependencies are inferred from the claim text.