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US 2015/0306072 A1Published application
Composition comprising melatonin or its derivatives with coenzyme q10 and use thereof against ageing of the skin
AssigneeUniversidad De Granada
InventorsGermaine ESCAMES ROSA, Darío ACUÑA CASTROVIEJO, Luis Carlos LÓPEZ GARCIA
Life of this patent
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Abstract
The invention relates to a composition comprising melatonin, a metabolite or derivative thereof and coenzyme Q10 and to use thereof for the production of a pharmaceutical or cosmetic composition for the treatment of the skin, said composition potentiating the movement of both molecules into the mitochondrion and facilitating percutaneous absorption, in which both the melatonin and the CoQ10 can reach all of the strata of the skin.
Claims15
1-55. (canceled)
A composition comprising:
- a) coenzyme Q10 at a concentration of 0.2 to 1.5% w/v with respect to the final composition,
- b) at least one compound of general formula (I),
- where:
- n is an integer between 1 and 4;
- R1 is a straight or branched (C1-C4) alkyl group;
- R2 is hydrogen, straight or branched (C1-C4) alkyl, a —C(═O)O—Ra group or a —C(═O)—N(H)—Ra group, wherein Ra is a straight or branched (C1-C4) alkyl group;
- and
- R3 is a hydrogen or a straight or branched (C1-C4) alkyl group;
- at a concentration of 1 to 5% w/v with respect to the final composition, and
- c) at least one antioxidant at a concentration of 0.25 to 0.75% w/v with respect to the final composition.
7 more elements
Dependencies are inferred from the claim text.