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US 2015/0306061 A1Published application
Method For Making Bismuth Containing Liquid Pharmaceutical Suspensions
AssigneeThe Procter & Gamble Company
InventorsSteven Ray Gilbert, Edward Paul Fitch, V, Derrick Ho, Daniel Jerome White, JR., Adam Michael Tunis
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Abstract
A method of producing a liquid pharmaceutical suspension by mixing magnesium aluminum silicate, gellan gum, bismuth subsalicylate, and methyl cellulose.
Claims12
A method of making a liquid pharmaceutical suspension comprising:
- a. mixing magnesium aluminum silicate with an aqueous media to form a first mixture;
- b. mixing gellan gum with the first mixture to form a second mixture;
- c. mixing a bismuth slurry with the second mixture to form a third mixture;
- d. mixing methyl cellulose with the third mixture to form a liquid pharmaceutical suspension.
1 more element
A method of making a suspension comprising:
- a. adding a suspension system component comprising a solid powder to an aqueous media to form a first mixture utilizing a hopper for containing the suspension system component, the hopper having a hopper inlet for receiving the suspension system component and a throat for distributing the suspension system component the throat comprises a throat inlet for receiving solids from the hopper and a throat outlet for discharging solids from the throat wherein a vertically oriented auger is disposed in the throat wherein the throat outlet is connected to a disperser at a connection and wherein the connection is substantially free of air;
- and
- b. adding an internal phase to form a suspension.
The method 5 wherein the suspension system comprises methyl cellulose and wherein the methyl cellulose is a powder.
A method of producing a suspension comprising:
- adding gellan gum to an ionic solution at ambient temperature.
Dependencies are inferred from the claim text.