US 2015/0306052 A1 · PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF FUNGAL INFECTIONS

Abstract

There is provided pharmaceutical compositions suitable for topical application to the nail for the treatment of nail diseases such as onychomycosis, comprising a urea-based component, a diol component, such as propylene glycol, an organic acid component, such as lactic acid, and a triol component, such a glycerol. There is further provided methods of improving the storage stability of a pharmaceutical composition suitable for topical application to the skin and/or nails comprising such urea-based components, diol components, organic acid components, and, optionally, an aqueous base, which method comprises adding a triol component, such a glycerol, to that composition prior to said storage.

Claims37

Dependent claims

1-20. (canceled)

Dependencies are inferred from the claim text.

Facts

Application

14/609,142Filed 29 Jan 2015

Priority

GB PCT/GB2013/05065415 Mar 2013

Published

29 Oct 2015

Term ends

Not estimatedThe source records don’t support an estimate.

Classification12 codes

A61K 31/19
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids: carboxylic acids, e.g. valproic acid
A61K 9/0014
Galenical forms characterised by the site of application: skin, i.e. galenical aspects of topical compositions
A61K 9/08
Medicinal preparations characterised by special physical form: solutions
A61K 31/047
Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates: having two or more hydroxy groups, e.g. sorbitol

Pharmaceutical composition for the treatment of fungal infections

Life of this patent

Pharmaceutical composition for the treatment of fungal infections

Life of this patent

Abstract

Claims37