Pharmaceutical compositions
AssigneeLocl Pharma, Inc.
InventorsPaul BOSSE, John AMELING, Bernard SCHACHTEL, Ray TAKIGIKU
Life of this patent
Estimating the term…
Abstract
Methods and compositions are provided which comprise effective amounts of analgesic to treat a subject, including reducing or eliminating an adverse effect associated with the analgesic.
Claims25
1-138. (canceled)
A solid composition, comprising an immediate-release layer that comprises an antiemetic, and a controlled-release layer that comprises an opioid analgesic and a non-opioid analgesic, wherein about 90% of the antiemetic is released in about 1 minute to about 20 minutes following contact of the solid composition with a dissolution fluid as measured by USP Apparatus 2 (Paddle Apparatus), and wherein 30-60% of the opioid analgesic is released in 5 to 10 minutes following contact of the solid composition with a dissolution fluid as measured by USP Apparatus 2 (Paddle Apparatus).
Dependencies are inferred from the claim text.