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US 2015/0305722 A1Published application
Cryogenic biopsy system and method
AssigneeRobin Medical, Inc.
InventorEREZ NEVO
Life of this patent
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Abstract
A cryogenic biopsy device is configured to provide tissue samples that are partially frozen and partially non-frozen. This enables histopathology analysis of the intact non-frozen part of the tissue sample and assessment of the in-vivo biomolecular state of the tissue that is stabilized and maintained in the frozen part of the sample. The device of the present invention may be used in rigid instruments and in flexible devices, such as endoscopes, for example, and may be suitable for single use or multiple use.
Claims18
A cryogenic biopsy device, the cryogenic biopsy device comprising:
- a cryogenic needle having a needle tip configured to penetrate a tissue to be sampled and configured to freeze a portion of the tissue;
- a cutting cannula coaxial to said cryogenic needle, said cutting cannula configured to cut said tissue;
- and
- a collection compartment adjacent to said cryogenic needle for collecting said cut tissue, wherein said device is configured to maintain a temperature gradient within the collected cut tissue.
1 more element
A biopsy system comprising:
- a cryogenic biopsy device, the device comprising:
- a cryogenic needle;
- a cutting cannula positioned coaxial to said cryogenic needle for providing a sliced sample of tissue;
- a collection compartment for collecting the sliced sample of tissue;
- and
- at least one sensor positioned within said collection compartment for sensing of a parameter within said collected sliced sample of tissue;
- and
- a processor, said processor comprising:
- a freezing unit for providing freezing material to said cryogenic needle;
- and
- a temperature gradient generator, for generating a temperature gradient within said collection compartment based on said sensed parameter.
8 more elements
Dependencies are inferred from the claim text.