Nutritional composition with non digestible oligosaccharides

A method for increasing the luminal fluid volume inside the small intestine of a subject, comprising administering to the subject a nutritional composition, which is not human milk, comprising protein, digestible carbohydrates, fat and one or more non-digestible oligosaccharides selected from of the group consisting of fructo-oligosaccharides, galacto-oligosaccharides, gluco-oligosaccharides, arabino-oligosaccharides, mannan-oligosaccharides, xylo-oligosaccharides, fuco-oligosaccharides, arabinogalacto-oligosaccharides, glucomanno-oligosaccharides, galactomanno-oligosaccharides, sialic acid comprising oligosaccharides and uronic acid oligosaccharides, wherein the non-digestible oligosaccharide is present in an amount of at least 2 wt. % based on dry weight of the nutritional composition and/or at least 0.4 g based on 100 ml of the nutritional composition.

A method of decreasing luminal protease activity or density in the intestine of a subject, for treating and/or preventing small bowel bacterial overgrowth in a subject, for increasing gastro-intestinal transit time in a subject and/or for decreasing the activity of toxins in the intestine of a subject, the method comprising administering to the subject one or more non-digestible oligosaccharides selected from the group consisting of fructo-oligosaccharides, galacto-oligosaccharides, gluco-oligosaccharides, arabino-oligosaccharides, mannan-oligosaccharides, xylo-oligosaccharides, fuco-oligosaccharides, arabinogalacto-oligosaccharides, glucomanno-oligosaccharides, galactomanno-oligosaccharides, sialic acid comprising oligosaccharides and uronic acid oligosaccharides and wherein the non-digestible oligosaccharide is present in an amount of at least 2 wt. % based on dry weight of the nutritional composition and/or at least 0.4 g based on 100 ml of the nutritional composition and wherein the nutritional composition is not human milk.