Method for producing 4-oxoquinoline compound
AssigneeJapan Tobacco Inc.
InventorsKoji Matsuda, Koji Ando, Shigeji Ohki, Jun-Ichi Hoshi, Takahiro Yamasaki
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Abstract
The present invention provides a compound useful as a synthetic intermediate for an anti-HIV agent having an integrase inhibitory activity, and a production method thereof, and a production method of an anti-HIV agent using the synthetic intermediate. Specifically, for example, a compound represented by the formula (2′): wherein R is a fluorine atom or a methoxy group, and R400 is a hydrogen atom or a C1-C4 alkyl group, or a salt thereof, and a production method thereof, and a production method of an anti-HIV agent using the synthetic intermediate.
Claims12
1-33. (canceled)
A compound of the following formula (7):
- wherein R100 is a C1-C4 alkyl group and R200 is a hydroxyl-protecting group.
A compound of the following formula (6)
- wherein R is a fluorine atom or a methoxy group, and R100 is a C1-C4 alkyl group.
A compound of the following formula (5):
- wherein R is a fluorine atom or a methoxy group, and R100 is a C1-C4 alkyl group.
A compound of the following formula (4):
- wherein R is a fluorine atom or a methoxy group, and R100 is a C1-C4 alkyl group,
- or a salt thereof.
A compound of the following formula (4-1-B):
- wherein R100 is a C1-C4 alkyl group,
- or a salt thereof.
A compound of the following formula (4-2-B):
- wherein R100 is a C1-C4 alkyl group,
- or a salt thereof.
A compound of the following formula (4-1-A):
- wherein R100 is a C1-C4 alkyl group,
- or a salt thereof.
A compound of the following formula (4-2-A):
- wherein R100 is a C1-C4 alkyl group,
- or a salt thereof.
A compound of the following formula (3):
- wherein R is a fluorine atom or a methoxy group.
A compound of the following formula (2′):
- wherein R is a fluorine atom or a methoxy group, and R400 is a hydrogen atom or a C1-C4 alkyl group,
- or a salt thereof.
A compound of the following formula:
Dependencies are inferred from the claim text.