Nutritional Composition for the Stimulation of Muscle Protein Synthesis
AssigneeN. V. Nutricia
InventorsMarion-Eve Adeline Jourdan, Yvette Charlotte Luiking, George Verlaan, Sovianne Ter Borg
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Abstract
The invention relates to the use of an anabolic amino acid derivative stimulus acting in combination with vitamin D for the manufacture of a medicament or nutritional composition for the prevention and/or treatment of a loss of any one of muscle mass, muscle strength, muscle function, and physical function, or any combination thereof, in a mammal.
Claims25
-20. (canceled)
A method for preventing or treating a loss of any one of muscle mass, muscle strength and muscle function, or any combination thereof, in an adult mammal, comprising administering to the adult mammal a nutritional composition comprising:
- (i) at least about 1 g leucine per 100 ml nutritional composition, of which at least about 20 weight % is in a free form, relative to the total amount of leucine;
- (ii) at least about 400 IU or 10 μg of vitamin D per 100 ml nutritional composition.
A nutritional composition comprising:
- (i) at least about 1 g leucine per 100 ml nutritional composition, of which at least about 20 weight % is in a free form, relative to the total amount of leucine;
- (ii) at least about 400 IU or 10 μg of vitamin D per 100 ml nutritional composition.
A method for improving the effect of leucine in the prevention or treatment of a loss of any one of muscle mass, muscle strength and muscle function, or any combination thereof, in an adult mammal, comprising administering to the adult mammal a nutritional composition comprising:
- (i) at least about 1 g leucine per 100 ml nutritional composition, of which at least about 20 weight % is in a free form, relative to the total amount of leucine;
- (ii) at least about 400 IU or 10 μg of vitamin D per 100 ml nutritional composition.
Dependencies are inferred from the claim text.