Staphylococcus aureus antigens
OwnerDavid Wyllie, Christine Rollier +3inventors
InventorsDavid Wyllie, Christine Rollier, Yuko Yamaguchi, Pauline Van Diemen, Adrian Hill
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Abstract
The present invention provides a non-replicating poxvirus vector comprising a nucleic acid sequence encoding a Staphylococcus aureus antigen, wherein the nucleic acid sequence encoding a Staphylococcus aureus antigen comprises a nucleic acid sequence having at least 70% sequence identity to a nucleic acid sequence selected from SEQ ID NOs: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, and 16. The present invention also provides compositions and uses of the vectors in methods of medical treatment.
Claims31
A non-replicating poxvirus vector, comprising a nucleic acid molecule encoding a Staphylococcus aureus antigen, wherein the nucleic acid molecule comprises a sequence having at least 70% sequence identity to a nucleic acid sequence selected from any one of SEQ ID NOs:
- 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, and 16.
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An adenovirus vector, comprising a nucleic acid molecule encoding a Staphylococcus aureus antigen, wherein the nucleic acid molecule comprises a sequence having at least 70% sequence identity to a nucleic acid sequence selected from any one of SEQ ID NOs:
- 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, and 16.
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-15. (canceled)
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-49. (canceled)
Dependencies are inferred from the claim text.