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US 2015/0217022 A1Published application
Nerve regeneration employing keratin biomaterials
AssigneeWake Forest University Health Sciences
InventorMark E. Van Dyke
Life of this patent
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Abstract
A keratin hydrogel matrix serves as an effective acellular scaffold for axonal regeneration and facilitates functional nerve recovery.
Claims23
A device for promoting the growth of a nerve in a mammal, comprising:
- a support structure having an elongate opening formed therein and configured for placement around a damaged region of a nerve;
- and
- a physiologically acceptable matrix composition in said opening, said matrix composition comprising a keratin.
A method for promoting the growth of a nerve in a mammal, comprising:
- encasing a damaged region of said nerve in a support structure having an elongate opening therein;
- and
- administering a physiologically acceptable matrix composition into said opening, said matrix composition comprising a keratin, in an amount effective to promote the growth of said nerve at said damaged region.
A kit comprising:
- (a) a support structure having an elongate opening formed therein and configured for placement around a damaged region of a nerve;
- (b) a container, wherein said support structure is packaged in said container sterile form;
- and
- (c) a physiologically acceptable matrix composition, wherein said matrix composition is sterile, and wherein said matrix composition comprises a keratin.
1 more element
Dependencies are inferred from the claim text.