Saturation assay
AssigneePlatform Diagnostics Limited
InventorsDouglas Robert EVANS, Gerald John ALLEN, Carolyn Jennifer RUDDELL
Life of this patent
Estimating the term…
Abstract
A modified form of saturation assay is provided that is based on the measurement of a free or unbound labelled reagent fraction (such that there is an increase in signal in the presence of analyte) and employs trapping zones to concentrate said unbound or free labelled faction to avoid loss of sensitivity. Preferably the assay is a membrane assay.
Claims20
A kit for performing a saturation assay for detection of an analyte in a sample, the kit comprising:
- a. a component for separating bound and unbound products of a competitive binding step;
- and
- b. a secondary trapping zone
A device for performing a saturation agglutination assay for detection of an analyte within a sample, the device comprising a carrier having a proximal end for receiving a sample, and a distal end toward which a sample may travel along the carrier, wherein the carrier comprises:
- a. a primary trapping zone comprising means which exclude an agglutinated fraction;
- and
- b. a secondary trapping zone comprising a component which excludes a labelled reagent.
Dependencies are inferred from the claim text.