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US 2015/0175686 A1Published application
Monoclonal Antibodies for Treatment of Cancer
AssigneesGanymed Pharmaceuticals AG, Johannes Gutenberg-Universitat Mainz
InventorsUgur Sahin, Michael Koslowski, Ozlem Tureci
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Abstract
The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing GT468, including tumor-related diseases such as breast cancer, lung cancer, gastric cancer, ovarian cancer, and hepatocellular cancer.
Claims25
1-35. (canceled)
An isolated antibody having the ability of binding to a peptide consisting of an amino acid sequence selected from the group consisting of SEQ ID NO:
- 3-10 and 35-79 and mediating inhibition of proliferation of cells expressing a protein comprising the amino acid sequence of SEQ ID NO:
- 2 and/or are characterized by association of a protein comprising the amino acid sequence of SEQ ID NO:
- 2 with the cell surface.
Dependencies are inferred from the claim text.