US 2015/0175646 A1 · SOLID FORMS OF AN ANTIVIRAL COMPOUND

Abstract

Crystalline solid forms of the anti-HCV compound (S)-isopropyl 2-((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphorylamino)propanoate (Compound I) are described Also provided are processes of making and methods of using the crystalline forms.

Claims10

Dependent claims

A crystalline Compound I

characterized by an XRPD spectrum comprising peaks at 12.6 and 13.5 °2θ±0.2° 2θ.

Dependencies are inferred from the claim text.

Facts

Application

14/563,639Filed 8 Dec 2014

Priority

23 Dec 2013

Published

25 Jun 2015

Term ends

Not estimatedThe source records don’t support an estimate.

Classification16 codes

C07H 19/10
Pyrimidine radicals: with the saccharide radical esterified by phosphoric or polyphosphoric acids
A61K 31/7052
Compounds having saccharide radicals and heterocyclic rings: having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
A61K 31/706
Having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides: containing six-membered rings with nitrogen as a ring hetero atom
A61K 31/7064
Containing six-membered rings with nitrogen as a ring hetero atom: containing condensed or non-condensed pyrimidines

Abstract

Claims10

Dependent claims

A crystalline Compound I

characterized by an XRPD spectrum comprising peaks at 12.6 and 13.5 °2θ±0.2° 2θ.

Dependencies are inferred from the claim text.

Solid forms of an antiviral compound

Life of this patent

Abstract

Claims10

Solid forms of an antiviral compound

Life of this patent

Abstract

Claims10