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US 2015/0174263 A1Published application
Compositions for treating cancer and methods for making the same
AssigneeThe Brigham and Women's Hospital, Inc.
InventorsShiladitya Sengupta, Ashish Kulkarni, Poornima Rao, Bhaskar Roy
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Abstract
Described herein are compositions and methods relating to chemotherapeutic agent conjugates and the treatment of cancer.
Claims24
-58. (canceled)
A composition comprising a conjugate, the conjugate comprising a chemotherapeutic agent conjugated to cholesterol.
The composition of any of claims 59-63, wherein the chemotherapeutic agent selected from the group consisting of:
- a PI3K inhibitor;
- PI103;
- P1828;
- LY294002;
- wortmannin;
- demethoxyviridin;
- IC486068;
- IC87114;
- GDC-0941;
- perifosine;
- CAL101;
- PX-866;
- IPI-145;
- BAY 80-6946;
- BEZ235;
- P6503;
- TGR1202;
- SF1126;
- INK1117;
- BKM120;
- IL147;
- XL765;
- Palomid 529;
- GSK1059615;
- ZSTK474;
- PWT33597;
- TG100-115;
- CAL263;
- GNE-447;
- CUDC-907;
- and AEZS-136.
28 more elements
Dependencies are inferred from the claim text.