Therapeutic method for treating congestive heart failure
AssigneeMadeleine Pharmaceuticals Pty Ltd
InventorThomas Robert Geimer
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Abstract
The present invention relates to a method of treating congestive heart failure (CHF) in a subject comprising administering a peptide derived from atrial natriuretic peptide (ANP) prohormone (eg vessel dilator; VSDL) or a mimetic thereof. In a particular application, the invention provides a method of treating the particular indication known as acute decompensated congestive heart failure (ADCHF). Devices for intravenous or subcutaneous infusion for use in the method of the invention are also disclosed.
Claims24
A method of treating chronic congestive heart failure (CHF) or acute decompensated congestive heart failure (ADCHF) in a subject, said method comprising administering to the subject an effective amount of vessel dilator (VSDL) or a mimetic thereof in the range of about 0.1 to 5 μg/kg/day.
A method of treating acute decompensated congestive heart failure (ADCHF) in a subject, said method comprising administering to the subject an effective amount of vessel dilator (VSDL) or mimetic thereof.
An infusion device containing, or provided with, a medicament comprising vessel dilator (VSDL) or a mimetic thereof adapted for infusion of the VSDL or mimetic, for treating chronic congestive heart failure (CHF) or acute decompensated congestive heart failure (ADCHF) in a subject, wherein said device is adapted to administer a dose of the VSDL or mimetic in the range of about 0.1 to 5 μg/kg/day.
Dependencies are inferred from the claim text.