Compositions and Methods for Treating Alzheimer's Disease and Other Tauopathies
AssigneeThe Board of Trustees of the Leland Stanford Junior University
InventorsBingwei Lu, Seongsoo Lee
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Abstract
Compounds, pharmaceutical compositions, and methods of using such compounds and compositions to treat or prevent Alzheimer's disease and related tauopathies through the inhibition of USP-9X and/or enhancement of SCF(β-TrCP).
Claims63
A composition for treating or preventing Alzheimer's disease and related tauopathies, the composition comprising a USP-9x inhibitor and a SCF(β-TrCP) enhancer.
A method for preventing or treating Alzheimer's disease and related tauopathies in an animal, the method comprising administering to the animal an effective amount of a composition comprising a USP-9x inhibitor and a pharmaceutically acceptable carrier thereof.
A kit comprising a USP-9x inhibitor and a pharmaceutically acceptable carrier thereof.
Dependencies are inferred from the claim text.