A composition selected from the group consisting of a pharmaceutical formulation, a nutritional formulation, a tube-feed formulation, a dietary supplement, a functional food, a beverage product and combinations thereof comprising a nutritional composition comprising:
- acid casein protein;
- vitamin K at a ratio of vitamin K1:K2 of between 3:1 to 1:3 and the vitamin K present in an amount of between 17.5 to 100 μg/100 g of the nutritional composition;
- vitamin D present in an amount of between 2.5 to 75 μg/100 g of the nutritional composition;
- and
- n6/n3 fatty acids at a ratio of n6:n3 fatty acids of between 5:1 to 1:5 and mixtures thereof.