Microparticles supporting cells and active substances
AssigneeInserm
InventorsClaudia Montero-Menei, Philippe Menei, Jean-Pierre Benoit, Valérie Tatard, Marie-Claire Venier
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Abstract
A method of repairing tissue includes implanting into a patient a therapeutically effective amount of a pharmaceutical composition including microparticles including a biodegradable, biocompatible material having cells of interest or fragments thereof adhered to at least a portion of a surface; and at least one substance active on the cells or their environment upon implantation of the microparticles in a patient associated with the material wherein the substances is released in a controlled or extended manner.
Claims38
A method of repairing tissue comprising implanting into a patient a therapeutically effective amount of a pharmaceutical composition comprising microparticles comprising a biodegradable, biocompatible material having cells of interest or fragments thereof adhered to at least a portion of a surface;
- and at least one substance active on the cells or their environment upon implantation of the microparticles in a patient associated with the material wherein the substance is released in a controlled or extended manner.
A method of transferring genes comprising administering a therapeutically effective amount of a pharmaceutical composition comprising microparticles comprising a biodegradable, biocompatible material having cells of interest or fragments thereof adhered to at least a portion of a surface;
- and at least one substance active on the cells or their environment upon implantation of the microparticles in a patient associated with the material wherein the substance is released in a controlled or extended manner.
A method of vaccinating against tumors comprising administering an effective amount of a vaccine comprising microparticles comprising a biodegradable, biocompatible material having cells of interest or fragments thereof adhered to at least a portion of a surface;
- and at least one substance active on the cells or their environment upon implantation of the microparticles in a patient associated with the material wherein the substance is released in a controlled or extended manner.
Dependencies are inferred from the claim text.