Triage scoring system
AssigneeThe Binding Site Group Limited
InventorsRichard Hughes, Stephen Harding
Life of this patent
Estimating the term…
Abstract
The application discloses a method of determining the severity of symptoms in a patient comprising (i) producing a triage score, such as an early warning score (EWS) modified early warning score (MEWS), paediatric early warning score (PEWS), NHS early warning score (NEWS), simple clinical score (SCS), rapid emergency score (REMS) or mortality in emergency department sepsis score for the patient, (ii) measuring an amount of free light chains (FLC), preferably combined free light chains (cFLC), in a sample from the patient, and (iii) using the triage score and the amount of FLC measured to assess the severity of symptoms in the patient. This also allows patients to be triaged to provide better treatment of them.
Claims21
A method of assessing the severity of symptoms in a patient comprising:
- (i) producing a triage score for the patient,
- wherein the triage score is selected from the group consisting of an early warning score (EWS), a modified early warning score (MEWS), a pediatric early warning score (PEWS), a NHS early warning score (NEWS), a simple clinical score (SCS), or a rapid emergency score (REMS),
- (ii) measuring an amount of free light chains (FLC), in a sample from the patient, and
- (iii) assessing the severity of symptoms in the patient based upon the triage score and the amount of FLC.
The method according to claim 13, wherein a measured amount of cFLC above 50 mg/L indicates an increased likelihood of death of the patient within 100 days without further treatment.
(canceled)
An assay kit comprising anti-FLC antibodies or fragments thereof, in combination with anti-albumin antibodies or fragments thereof, for use in a method according to claim 11.
Dependencies are inferred from the claim text.