Detecting Neuronal Action Potentials Using a Convolutive Compound Action Potential Model
AssigneeMED-EL Elektromedizinische Geraete GmbH
InventorsStefan Strahl, Konrad Schwarz, Angelika Dierker, Philipp Spitzer
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Abstract
A system and method detect neuronal action potential signals from tissue responding to electrical stimulation signals. A compound discharge latency distribution (CDLD) of the neural tissue is derived by deconvolving a tissue response measurement signal taken responsive to electrical stimulation of the neural tissue by a stimulation electrode, with an elementary unit response signal representing voltage change at a measurement electrode due to the electrical stimulation. The CDLD is compared to known physiological data to detect an NAP signal from the tissue response measurement signal.
Claims18
A system for detecting a neuronal action potential (NAP) signal from electrically stimulated neural tissue, the system comprising:
- a physiological database containing physiological data characterizing neural tissue response to electrical stimulation;
- and
- a response measurement module configured to:
- i. derive a compound discharge latency distribution (CDLD) of the neural tissue by deconvolving:
- (a) a tissue response measurement signal taken responsive to electrical stimulation of the neural tissue by a stimulation electrode, with
- (b) an elementary unit response signal representing voltage change at a measurement electrode due to the electrical stimulation;
- ii. compare the CDLD to physiological data from the physiological database to detect an NAP signal from the tissue response measurement signal;
A method for detecting a neuronal action potential (NAP) signal from electrically stimulated neural tissue, the method comprising:
- deriving a compound discharge latency distribution (CDLD) of the neural tissue by deconvolving:
- i. a tissue response measurement signal taken responsive to electrical stimulation of the neural tissue by a stimulation electrode, with
- ii. an elementary unit response signal representing voltage change at a measurement electrode due to the electrical stimulation;
- comparing the CDLD to known physiological data to detect an NAP signal from the tissue response measurement signal.
Dependencies are inferred from the claim text.