Rapid specific pathogen free animal
AssigneeBiovalence Sdn. Bhd.
InventorsEng Huan Ung, Ag., Muhammad Sagaf Abu Bakar
Life of this patent
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Abstract
A method of producing at least one specific pathogen free (SPF) non-human animal and/or a method of producing at least one specific pathogen resistant (SPR) non-human animal, the method comprising administration of a fusion protein to the surviving animal wherein the fusion protein comprises at least one polypeptide B which is a Type 1 Ribosome Inactivating Protein (RIP) or fragment thereof; and (i) at least one polypeptide A which is an Antimicrobial peptide; and/or (ii) at least one polypeptide C which is a Cationic Antimicrobial Peptide (CAP) or fragment thereof.
Claims28
A method of producing at least one specific pathogen free (SPF) non-human animal, the method comprising:
- (a) selecting a surviving animal in an environment comprising at least one pathogen that is capable of infecting and/or killing the animal;
- (b) administration of a fusion protein to the surviving animal wherein the fusion protein comprises at least one polypeptide B which is a Type 1 Ribosome Inactivating Protein (RIP) or fragment thereof;
- and
- (i) at least one polypeptide A which is an Antimicrobial peptide;
- and/or
- (ii) at least one polypeptide C which is a Cationic AntiMicrobial Peptide (CAP) or fragment thereof;
- and
- (c) resulting surviving animal is the SPF non-human animal.
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Dependencies are inferred from the claim text.