# US 2015/0147802 A1 · Cleaning agent composition for medical-instrument cleaner > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2015/0147802 A1 - Document ID: US20150147802A1 - Status: Published application - Kind: A1 - Application number: 14/404,388 - Filed: 2013-05-28 - Published: 2015-05-28 - Earliest claimed: 2012-05-28 - Assignees: Kao Corporation - Applicants: Kao Corporation - Inventors: Masaya Nishio - Web page: https://patentgrep.com/patent/US20150147802A1 ## CPC - C11D 1/835: Mixtures of non-ionic with cationic compounds - C11D 1/86: Mixtures of anionic, cationic, and non-ionic compounds - C11D 3/386: Preparations containing enzymes {, e.g. protease or amylase} - C11D 1/04: Carboxylic acids or salts thereof (soap C11D9/00) - C11D 1/722: Ethers of polyoxyalkylene glycols having mixed oxyalkylene groups; {Polyalkoxylated fatty alcohols or polyalkoxylated alkylaryl alcohols with mixed oxyalkylele groups (C11D1/721 takes precedence)} - C11D 2111/14: Hard surfaces - C11D 2111/20: Industrial or commercial equipment, e.g. reactors, tubes or engines - C11D: DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL ## Abstract The present invention relates to [1] a detergent composition for a washer for medical devices, including a nonionic surfactant (A) represented by the following formula (1), at least one compound (B) selected from the group consisting of fatty acids having not less than 6 and not more than 10 carbon atoms or salts thereof, a cationic surfactant (C) represented by the specific formula, and water; and [2] a method of washing a medical device using a washer for medical devices which includes the step of washing the medical device with a mixture including the above detergent composition and an enzyme. The present invention provides a detergent composition for a washer for medical devices which is less foamed even when used at a low temperature and is excellent in washability and storage stability, and a method of washing a medical device using a washer for medical devices, RO-[(EO)m/(PO)n]—H (1) wherein R represents an alkyl group having not less than 6 and not more than 18 carbon atoms; EO represents an ethanediyloxy group; PO represents a propanediyloxy group; m and n each represent an average molar number of addition of the ethanediyloxy or propanediyloxy group, and are each independently a number of not less than 1 and not more than 20; and the mark “/” represents that EO and PO may be added either in a random form or in a block form, and an order of addition of EO and PO is optional. ## Claims ### Claim 1 A detergent composition for a washer for medical devices, comprising a nonionic surfactant (A) represented by the formula (1) which is contained in the composition in an amount of not less than 1% by mass and not more than 40% by mass; at least one compound (B) selected from the group consisting of fatty acids having not less than 6 and not more than 10 carbon atoms and salts thereof which is contained in the composition in an amount of not less than 1% by mass and not more than 20% by mass in terms of a fatty acid; a cationic surfactant (C) represented by the formula (2); and water, the nonionic surfactant (A) being present in an amount of not less than 90% by mass on the basis of a total amount of whole nonionic surfactants contained in the detergent composition, a mass ratio of the at least one compound (B) selected from the group consisting of fatty acids having not less than 6 and not more than 10 carbon atoms and salts thereof to the cationic surfactant (C) [(B)/(C)] being not less than 20 and not more than 3000, and the detergent composition having a pH value of not less than 10 as measured at 25° C., RO-[(EO)m/(PO)n]—H (1) wherein R represents an alkyl group having not less than 6 and not more than 18 carbon atoms; EO represents an ethanediyloxy group; PO represents a propanediyloxy group; m and n each represent an average molar number of addition of the ethanediyloxy or propanediyloxy group, and are each independently a number of not less than 1 and not more than 20; and the mark “/” represents that EO and PO may be added either in a random form or in a block form, and an order of addition of EO and PO is optional, and N+(R1)(R2)(R3)(R4).X− (2) wherein R1, R2, R3 and R4 are each independently an alkyl group having not less than 1 and not more than 24 carbon atoms or a benzyl group; and X− is a monovalent anion. ### Claim 2 (depends on 1) The detergent composition for a washer for medical devices according to claim 1, wherein a mass ratio of a content of the nonionic surfactant (A) to a content of the at least one compound (B) selected from the group consisting of the fatty acids and the salts thereof [(A)/(B)] is not less than ⅕ and not more than 5. ### Claim 3 (depends on 1) The detergent composition for a washer for medical devices according to claim 1, wherein R in the formula (1) is a branched-chain alkyl group having not less than 6 and not more than 18 carbon atoms. ### Claim 4 (depends on 1) The detergent composition for a washer for medical devices according to claim 1, wherein EO and PO in the formula (1) are in the form of a random adduct thereof. ### Claim 5 (depends on 1) The detergent composition for a washer for medical devices according to claim 1, wherein the cationic surfactant (C) is at least one compound selected from the group consisting of alkyl dimethyl benzyl ammonium chlorides and salts thereof. ### Claim 6 (depends on 1) The detergent composition for a washer for medical devices according to claim 1, further comprising an alkaline agent (D). ### Claim 7 (depends on 6) The detergent composition for a washer for medical devices according to claim 6, wherein the alkaline agent (D) is an alkanolamine. ### Claim 8 (depends on 1) The detergent composition for a washer for medical devices according to claim 1, further comprising a chelate agent (E). ### Claim 9 (depends on 1) The detergent composition for a washer for medical devices according to claim 1, wherein the medical device is an endoscope. ### Claim 10 (depends on 1) A method of washing a medical device using a washer for medical devices comprising the step of washing the medical device with a mixture comprising the detergent composition for a washer for medical devices as claimed in claim 1, and an enzyme. ### Claim 11 (depends on 1) A method of washing a medical device using a washer for medical devices comprising the step of washing the medical device with a mixture comprising the detergent composition for a washer for medical devices as claimed in claim 1, and an enzyme; wherein the detergent composition for a washer for medical device is diluted with water not less than 50 times by mass and not more than 1000 times by mass upon use. ### Claim 12 (depends on 10) The method of washing a medical device using a washer for medical devices according to claim 10, wherein the enzyme is a protease. ### Claim 13 (depends on 12) The method of washing a medical device using a washer for medical devices according to claim 12, wherein the protease is an alkaline protease, and a washing solution containing the alkaline protease having a proteolytic activity of not less than 0.01 PU/L and not more than 200 PU/L is prepared and used for washing the medical device. ### Claim 14 (depends on 13) The method of washing a medical device using a washer for medical devices according to claim 13, wherein the washing solution is circulated and reused for washing the medical device. ### Claim 15 (depends on 10) The method of washing a medical device using a washer for medical devices according to claim 10, wherein the medical device is an endoscope.