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US 2015/0104475 A1Published application
Compositions and methods related to viral vaccines
AssigneeThe Ohio State University
InventorDaral John Jackwood
Life of this patent
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Abstract
Provided herein are methods and compositions relating to Infectious Bursal Disease Virus (IBDV), and vaccines for treatment and prevention thereof.
Claims50
A polyvalent VP2 of infectious bursa disease virus (IBDV) or fragment thereof, wherein the VP2 is a trimer comprised of three VP2 monomers, or trimer forming fragments thereof.
A polyvalent VP2 of IBDV, wherein the polyvalent VP2 has the following formula:
- R1-R2-R3, wherein R1-R2-R3 are each monomers, and at least one of R1, R2 and R3 is an antigenically distinct monomer from the other monomers.
A mosaic virus like particle (VLP) comprising a VP2 trimer that is antigenically distinct from at least one VP2 trimer in the VLP.
Dependencies are inferred from the claim text.