Canine circovirus sequences and uses thereof
AssigneeThe Trustees of Columbia University in the City of New York
InventorsW. Ian Lipkin, Amit Kapoor, Edward J. Dubovi
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Abstract
The invention is directed to a isolated a canine circoviruses associated with canine respiratory and gastrointestinal disease, and isolated nucleic acids sequences and polypeptides thereof. The invention also relates to antibodies against antigens from canine circoviruses. The invention also relates to iRNAs which target nucleic acid sequences of the canine circovirus. The invention is related to methods for detecting the presence or absence of canine circoviruses in an animal. The invention is also related to immunogenic compositions for inducing an immune response against canine circoviruses in an animal.
Claims26
An isolated nucleic acid having the sequence of SEQ ID NO:
- 1.
An isolated nucleic acid having at least about 60% sequence identity to SEQ ID NO:
- 1.
An isolated nucleic acid which comprises at least 10 consecutive nucleotides of SEQ ID NO:
- 1.
An isolated nucleic acid which comprises at least 10 consecutive nucleotides of a sequence having at least about 60% identity to SEQ ID NO:
- 1.
An isolated polypeptide having the sequence of any of SEQ ID NOs:
- 2-4.
An isolated polypeptide having at least about 80% sequence identity to any of SEQ ID NO:
- 2-4.
An isolated polypeptide comprising at least 8 consecutive amino acids of any of SEQ ID NOs 2-4.
An isolated polypeptide comprising at least 8 amino acids having at least about 80% identity to the sequence of any of SEQ ID NOs 2-4.
Dependencies are inferred from the claim text.