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US 2015/0090592 A1Published application
Split-sensor dielectrophoretic/magnetophoretic cytometer
AssigneeUniversity of Manitoba
InventorsDouglas Thomson, Gregory Bridges, Michael Butler, Marija Nikolic-Jaric, Elham Salimi, Tim Cabel, Szymon Rzeszowski, Graham Ferrier, Katrin Braasch
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Abstract
Embodiments of an improved sensor for dielectrophoretic cytometry are presented. In one embodiment, the sensor includes a plurality of sensor electrodes as well as an actuation electrode. Embodiments of microfluidic systems incorporating such sensor are also described. Additionally, embodiments of methods or performing cytometry analysis are also presented.
Claims25
An apparatus comprising:
- a first sensor electrode configured to sense a physical property of an analyte at a first time;
- a second sensor electrode configured to sense a physical property of an analyte at a second time;
- and
- an actuation electrode disposed between the first sensor electrode and the second sensor electrode and configured to apply an actuation force to one or more objects in the analyte.
1 more element
A system comprising:
- a fluid inlet configured to receive an analyte fluid comprising one or more objects;
- a fluid outlet configured to dispense of the analyte fluid;
- a sensor element comprising:
- a first sensor electrode configured to sense a physical property of the analyte fluid at a first time;
- a second sensor electrode configured to sense a physical property of an analyte fluid at a second time;
- and
- an actuation electrode disposed between the first sensor electrode and the second sensor electrode and configured to apply an actuation force to one or more objects in the analyte fluid;
- and
- a fluid channel coupling the fluid inlet to the fluid outlet, and configured to provide at least a portion of the analyte fluid to the sensor element.
6 more elements
A method comprising:
- sensing a physical property of an object in an analyte fluid with a first sensor electrode at a first time;
- applying an actuation force to the object in the analyte fluid;
- and
- sensing the physical property of the object in the analyte fluid with a second sensor electrode at a second time.
1 more element
Dependencies are inferred from the claim text.